ݔ௠|?,

⋯ݕ௡|? ሻൌmin ቐ

݀௠௡൅ߜሺݔ௠ାଵ, ݕ௡ାଵሻ

݀௠௡൅ߜሺെ,

ݕ௡ାଵሻ

݀௠௡൅ߜሺݔ௠ାଵ

, െሻ

(7.10)

Sellers table is shown in Table 7.2 for aligning two sequences

T and y=TGCT. Sequence x was placed vertically and sequence y

ed horizontally. All cells were indexed by the top row and the far

mn. For instance, the cell of the first residue (T) of sequence x and

esidue (T) of sequence y was indexed or denoted by (1, 1). Note

ght panel of the table was used for indicating the optimal moving

for each cell.

Table 7.2. The Sellers table for initialisation of an alignment.

0

1

2

3

4

1

2

3

4

-

T

G

C

T

T

G

C

T

-

0

1

2

3

4

T

1

G

2

G

3

C

4

T

5

initial stage shown in Table 7.2, the alignment cost (distance)

ulated when aligning residues of two sequences with gaps. The

of the table, which was below sequence y, was for inserting gaps

ence x. When align the first residue of sequence y (T) with a gap,

was inserted into sequence x. Because of this, one unit of penalty

ied. Therefore the cell (0, 1) was filled by a one. When align the

residues of sequence y (TG) with two gaps, two penalties were

ecause two gaps were inserted into sequence x. Similarly, the cell

s filled by a two. The third column from left, which was beside

x of the table represented the cost when align the residues of

x with gaps. Similarly, when aligning the first residue of

x (T) with a gap, a unit penalty was applied because a gap was